In the marrow there are three granulocytic series of the leukocytes. There are Eosinophils, Neutrophils and Basophils which synthesize proteins and store them as cytoplasmic granules. The appearance of specific granules marks the progression of promyelocyte to neutrophilic, eosinophilic and microbial killing.
Neutrophils are the type of white blood cells which granulocytes are responsible for engulfing bacteria on the extracellular Matrix through phagocytosis. During phagocytosis a vesicle phagosome is formed from the plasma membrane surrounding the bacterium in the extracellular matrix. The waste formed during digestion is released by a process known as exocytosis. The neutrophils are the first cell that migrate to the site experiencing inflammation using cytokines signals. The process of migration is called Chemotaxis.
Basophils are they last group of white blood cells which granulocytes prevents quick blood clotting as they contain heparin. They are also the largest granulocytes. Basophils are capable of serving as phagocytes as well. This granulocytes release serotonin and histamine for inducing inflammation, these cells play a vital role when it comes to fighting a viral infection. Basophilia is the disease type associated with Basophils which is rarely found with leukaemia.
Difference between Neutrophils and Basophils:
|Neutrophils consists of multilobed nucleus||Basophil consists of Bean shaped nucleus|
|Neutrophils are natural pink in color||Basophils are dark blue in color|
|Neutrophils engulf bacteria found in the extracellular matrix through phagocytosis||Basophils contain heparin that helps to prevent quick clotting of the blood|
|Neutrophils lifespan is 5 -90 hours||Basophils lifespan is 60- 70 hours|
|40 - 75% of white blood cells||0.5 to 1% of white blood cells|
|Neutrophils size is 8.85 μm||Basophils size is 10 - 14 μm|
|Neutrophils granules contain lysozyme, A2, acid hydrolyses, elastase etc.,||Basophils granules contain histamine, heparin and chondroitin.|
Neutrophils, Eosinophils and Basophils are formed during hematopoiesis. These granulocytes are known as myeloid cells. Granulocytes are produced in the bone marrow and circulated in the blood to provide defence against bacteria viruses and parasites.
The main difference between Neutrophils, Eosinophils and Basophils are their structure and their role in the body of vertebrates. Granulocytes and Lymphocytes collectively from the group of cells called the white blood cells.
If you want to read more about Difference between Antigen and Antibodies click here.